
黄小阳,江西吉安人,中共党员,博士。研究方向为心血管药理学研究。参与国家级等科研项目2项,发表论文10余篇。
主要学习与研究经历:
2023/08–湖南医药学院,药学院,教师;
2018/09–2023/07,重庆大学,药学院,博士
2015/06–2018/07,百奥泰生物科技(广州)有限公司,抗体研发工程师
2012/09–2015/06,中山大学,药学院,硕士
2008/09–2012/06,黑龙江大学,生命科学学院,学士
主要学术成果情况:
1. Huang XiaoYang, Tong Xiaoyong, et al. Substitution of SERCA2 Cys 674 aggravates cardiac fibrosis by promoting the transformation of cardiac fibroblasts to cardiac myofibroblasts. Biochem Pharmacol[J]. Biochem Pharmacol, 2022 Sep;203:115164.
2. Huang XiaoYang, Zeng Zhenhua, Tong Xiaoyong, et al. The therapeutic strategies targeting mitochondrial metabolism in cardiovascular disease. Pharmaceutics[J]. 2022, 14(12),2760.
3. 参加“第十三届海峡两岸心血管科学研讨会暨第七届中国酒城国际心血管医学学术会议”荣获“埃德杯青年论坛”报告二等奖。
4. Zeng Zhenhua, Zhou Xia, Zhu Yanru, Huang Xiaoyang, et al. Krüppel-like Factor 7 inhibits proliferation and migration of pulmonary smooth muscle cells via p21 activation. Europen Journal of Phamacology[J].2023 Feb 5;940:175473.
5. Tang Weijia, Huang Xiaoyang, et al. Compounds and methods for the treatment of TROP2 positive diseases[P]. PCT patent: WO2019029715(A1); US11192954(B2); AU2018267660(B2); HK1261668(A1); EP3464381(A1); CA3038423(A1); JP2020503243A; NZ752091.
6. 汤伟佳 ,黄小阳 ,俞金泉,等. Trop2阳性疾病治疗的化合物及方法[P]. 中国专利: CN111087471B, CN109078181B,CN111018992B.
7. 黄小阳, 李卓明, 刘志平, 等. SIRT6 通过调节 eNOS 抑制心肌肥大的机制研究[J]. 中山大学学报: 医学科学版, 2015, 36(3): 338-345.
8. Liu X P, Gao H, Huang Xiaoyang, et al. Peroxisome proliferator–activated receptor gamma coactivator 1 alpha protects cardiomyocytes from hypertrophy by suppressing calcineurin-nuclear factor of activated T cells c4 signaling pathway[J]. Translational Research, 2015, 166(5): 459-473. e3.
9. Liu Z, Xu S, Huang Xiaoyang, et al. Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E‐deficient mice: role of lectin‐like oxidized LDL receptor‐1[J]. British journal of pharmacology, 2015, 172(23): 5661-5675.
10. Liu Z, Wang J, Huang Xiao Yang, et al. Deletion of sirtuin 6 accelerates endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice[J]. Translational Research, 2016, 172: 18-29. e2.